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Examination of Motor and Cognitive Planning in People with Parkinson's Disease
Official Study Title: Investigations of pre-motor processing during speech production
Sponsor: NIH/National Institute of Deafness and Other Communication Disorders
Clinicaltrials.gov ID:
Study ID:
Summary
This study will examine how the brain gets ready to give a response. Two areas in particular that have been shown to be especially difficult for some people with Parkinson's disease Parkinson's DiseaseA chronic, slowly progressive disease of the nervous system characterized by the combination of tremor, rigidity, bradykinesia and stooped posture, among other symptoms. (PD) are (1) quickly switching between movements or thoughts or (2) holding on to the "planning" of a movement or thought over time. To understand these processes, the investigator uses reaction time tasks (e.g., reaction time to say a word or press a button). Participants are asked complete one reaction time session while off of their PD medications for 15 hours. Participants also complete tests of language, memory and other higher level cognitive CognitiveRelated to mental activities having to do with perception, memory, judgment, and reasoning. functions. The study involves three sessions that are conducted on the University of Washington campus.
Study Phase
Not Applicable
What is a study phase?
Symptoms Addressed: Study does not address symptoms
Study does not address symptoms
Time Commitment
- Less than one month
- 3 sessions for participants with PD; 2 sessions for control participants. (1st session = approx 2 hours, 2nd and 3rd sessions = approx 1.5 hours)
Eligibility
- Gender(s) Accepted: Either
- Study is enrolling non-PD participants
Inclusion Criteria
- Native English speaker
- Adequate hearing and vision
- Currently taking PD medications
Exclusion Criteria
- Neurological problems aside from PD (e.g., history of stroke, seizure disorder, head injury etc.)
Enrollment
Expected Enrollment: 70 (US)
Date Enrollment Began: Jul 01 2007
Last Updated Date: Jan 02 2008
Trial Post Date: Jan 02 2008
Website:
Primary Contacts and Locations
Washington
- Kristie Spencer — Primary Investigator
University of Washington
kas@u.washington.edu
Phone: 206-543-7980
1417 NE 42nd Street
Seattle, WA 98105
USA
