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Participant Stories

“I participate because it is the right thing to do, for myself, for my children, and for the millions of people who have Parkinson’s disease.  Without participation there will be no cure.” –Mike, Diagnosed 7 years

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Recently Diagnosed with Parkinson's Disease?

If you have recently been diagnosed with Parkinson’s disease (PD) understanding the disease, and learning about the resources available to you, are good first steps.

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Browse by Clinical Symptom

Some clinical studies address Parkinson's symptoms. These symptoms are often separated into two categories: movement symptoms and non-movement symptoms.

Movement symptoms include most of the physical symptoms of PD, such as balance, rigidity, tremor, freeze attacks, uncontrollable movements (dyskinesia), slowness of movement (bradykinesia), walking/gait, postural difficulties, writing difficulty, and general loss of motor skills.

Non-movement symptoms include the psychological and emotional symptoms of PD, and some non-motor bodily symptoms, such as anxiety or depression, cognitive mood swings, dementia, sense of smell, vision, memory, weight loss, psychosis, sleep disturbances, hallucinations, swallowing difficulty (dysphagia), muscle pain, masked face, speech problems and loss of energy.

Some clinical studies are designed to investigate potential therapies that address both movement and non-movement symptoms.

There are also studies that do not address PD symptoms. These studies may be observational studies that are examining the nature of the disease or new testing methods, some may be examining a potentially neuroprotective agent (one that slows the progression of the disease), and some may be genetic studies, looking at the hereditary factors in Parkinson's.

To view a list of trials by symptom category, use the drop-down menu below.

Study enrolling people without Parkinson's

Search Results: Movement and Non-movement

15 trials found. Displaying results 1-10

Date Posted: Study Title: Locations: Type of Study: Symptoms Addressed:
Jan 15 2012 UPDATED*: A Study to Assess the Clinical Effect of Droxidopa in the Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Participants with Parkinson's Disease AL, AZ, CA, CT, FL, GA, IL, LA, MA, MI, MS, NC, NJ, NV, NY, OH, OK, PA, TX, UT, VA Intervention General PD symptoms, Balance, Postural difficulties
Oct 12 2011 Accepts Healthy Participants Pioglitazone in Early Parkinson Disease (FS-ZONE) AL, CA, CO, CT, FL, GA, HI, IL, KS, KY, LA, MA, MD, MI, MN, MO, NC, NH, NY, OR, PA, SC, TN, TX, VA, VT Intervention General PD symptoms
Sep 09 2011 Extended Release Amantadine Safety and Efficacy Study in Levodopa-induced Dyskinesia (EASED Study) CA, CT, FL, GA, IL, KS, MA, MI, NC, NJ, OK, TN, TX, WA Intervention Uncontrollable movements (Dyskinesia), General PD symptoms
Aug 02 2011 Integrated Exercise: Balance Work to Improve Parkinson’s Postural Stability NY Intervention Walking/Gait, Slowness of movement (bradykinesia), Rigidity, Postural difficulties, General PD symptoms, Balance
May 12 2011 Studies of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Participants - Still Enrolling! AL, CA, CO, DC, FL, IL, KY, MD, MO, NC, NY, OH, VT, WA Intervention Freeze Attacks, General PD symptoms, Loss of Motor Skills, Muscle Pain, Rigidity, Uncontrollable movements (Dyskinesia), Walking/Gait
Apr 25 2011 Investigation of Cogane™, an Oral Neurotrophic Factor Inducing Drug: Potential Early-stage Novel Therapy for Parkinson's Disease (CONFIDENT-PD) AB, AZ, CA, CO, CT, FL, GA, ID, IL, KS, MA, MI, MN, MO, NC, NY, OH, ON, PA, QC, SC, SK, TN, TX, WI Intervention Walking/Gait, Tremor, Speech problems (hypophonic), Slowness of movement (bradykinesia), Sleep disturbances, Sexual Difficulties, Rigidity, Postural difficulties, Memory, Loss of Motor Skills, General PD symptoms, Depression, Dementia, Cognitive Moods, Balance, Anxiety
Mar 29 2011 Accepts Healthy Participants A Study to Evaluate Changes in Energy Expenditure Between Corrected and Natural Walking Pace on a Treadmill in People with Parkinson's Disease NY Intervention General PD symptoms, Loss of Energy, Slowness of movement (bradykinesia), Walking/Gait
Mar 07 2011 Magnetic Stimulation for the Treatment of Motor and Mood Symptoms of Parkinson’s Disease CA, FL, MA, ON Intervention Depression, Cognitive Moods, Balance, Anxiety, Freeze Attacks, General PD symptoms, Loss of Motor Skills, Masked Face, Memory, Rigidity, Slowness of movement (bradykinesia), Tremor, Uncontrollable movements (Dyskinesia), Walking/Gait
Oct 27 2010 Study of the Efficacy and Safety of Trimethobenzamide (Tigan®) in the Control of Nausea and Vomiting During Treatment with Apomorphine (Apokyn®) for Intermittent “Off” Episodes AZ, CA, FL, GA, IA, IL, MI, NC, NY, OH, TX, VA Intervention Freeze Attacks, General PD symptoms, Loss of Motor Skills, Nausea, Slowness of movement (bradykinesia)
Jun 23 2010 Study of the Safety and Clinical Utility of IPX066 in Subjects With Parkinson's Disease AL, AR, AZ, CA, FL, IL, MI, NC, NJ, NY, OH, OK, ON, QC, SC, TX, WA, WI Intervention Balance, General PD symptoms, Loss of Motor Skills, Postural difficulties, Rigidity, Slowness of movement (bradykinesia), Uncontrollable movements (Dyskinesia), Walking/Gait
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